Tanoto Foundation Professorships

Professor Stuart Cook
Cardiovascular Medicine

A recipient of the President's Technology Award in Singapore in 2018, Professor Cook is a leading cardiovascular research expert, having done extensive work in human genetics, heart muscle disease and cardiac imaging. He heads a crossdisciplinary research team at Duke-NUS and the National Heart Research Institute to identify new genes and pathways for heart disease, for better therapeutic targets. Professor Cook led a study in Singapore to find out whether mutations in the titin gene are responsible for heart muscle weakness in Asians. This discovery catalyzed the development of a commercially available, next-generation test kit. The heart-testing device he helped to create in Singapore is used by 10,000 patients a year all over the world.

Professor Lim Soon Thye
Medical Oncology

Professor Lim’s research focuses on T cell and NK-cell lymphomas because they are more common in Asia compared to the West and are more fatal than B cell lymphomas, yet they are less well studied and treatment options are currently limited. His discovery of genetic mutations associated with T and NK-cell lymphomas has opened up a potential new treatment that targets genetic mutations and reactivates the body’s natural defenses to fight lymphoma cells. He will also continue with epidemiological studies where several of his diagnostic and algorithmic platforms, when validated, can be incorporated into routine clinical workflows in hospital systems.

Professor Karl Tryggvason
Diabetes

Professor Tryggvason’s research findings in gene variants led to the identification of novel genes that may enable scientists and clinicians to identify diabetic patients that are more likely to be affected by kidney, eye, and general blood vessel diseases. Prof Tryggvason’s expertise lies in the structure and function of human cells and how they interact with the extracellular matrix, a complex mesh of proteins and structures which surrounds and connects human cells. In addition, much of the knowledge gained through Prof Tryggvason’s work on diabetes can be modified and are applied to other serious illnesses.
Tanoto Foundation Professor until 2024